The Dietary Science Foundation
Telephone:+46 70-750 22 16
269 39 Båstad
Abdominal obesity, prediabetes, and type 2 diabetes carry an increased risk for cancer. One likely explanation for the risk increase is that high insulin levels in the blood trigger the body’s growth system. Theoretically, a diet that lowers insulin levels could help more people survive their cancer. The Dietary Science Foundation wants to investigate this through well-constructed scientific studies.
Someone who has abdominal fat, prediabetes or type 2 diabetes can have ten times more insulin in their blood after a meal than a healthy person. Insulin not only lowers blood sugar but also stimulates cell growth. In addition, insulin activates another important growth factor in the body: IGF-1. Most cancer cells have receptors for both insulin and IGF-1 on their surfaces. When growth factors attach to these receptors, the cells are given a signal that they should grow.
This biochemical mechanism may explain why people with abdominal fat, prediabetes and type 2 diabetes have a higher risk of getting certain kinds of cancer, and why it’s often a more aggressive form.
There are studies that suggest that dietary glycemic index might affect the development of cancer, but they are too few and too small. The research needs to be strengthened. If you want to support our fight against cancer, please join us as a one-time or monthly donor. In this way, you help us in our long-term efforts.